Thursday, November 22, 2012

Cartilage made easy with novel hybrid printer

ScienceDaily (Nov. 22, 2012) ? The printing of three-dimensional tissue has taken a major step forward with the creation of a novel hybrid printer that simplifies the process of creating implantable cartilage.

The printer has been presented Nov. 22, in IOP Publishing's journal Biofabrication, and was used to create cartilage constructs that could eventually be implanted into injured patients to help re-grow cartilage in specific areas, such as the joints.

The printer is a combination of two low-cost fabrication techniques: a traditional ink jet printer and an electrospinning machine. Combining these systems allowed the scientists to build a structure made from natural and synthetic materials. Synthetic materials ensure the strength of the construct and natural gel materials provide an environment that promotes cell growth.

In this study, the hybrid system produced cartilage constructs with increased mechanical stability compared to those created by an ink jet printer using gel material alone. The constructs were also shown to maintain their functional characteristics in the laboratory and a real-life system.

The key to this was the use of the electrospinning machine, which uses an electrical current to generate very fine fibres from a polymer solution. Electrospinning allows the composition of polymers to be easily controlled and therefore produces porous structures that encourage cells to integrate into surrounding tissue.

"This is a proof of concept study and illustrates that a combination of materials and fabrication methods generates durable implantable constructs," said James Yoo, M.D., Ph.D., Professor at the Wake Forest Institute for Regenerative Medicine, and an author on the study. "Other methods of fabrication, such as robotic systems, are currently being developed to further improve the production of implantable tissue constructs."

In this study, flexible mats of electrospun synthetic polymer were combined, layer-by-layer, with a solution of cartilage cells from a rabbit ear that were deposited using the traditional ink jet printer. The constructs were square with a 10cm diagonal and a 0.4mm thickness.

The researchers tested their strength by loading them with variable weights and, after one week, tested to see if the cartilage cells were still alive.

The constructs were also inserted into mice for two, four and eight weeks to see how they performed in a real life system. After eight weeks of implantation, the constructs appeared to have developed the structures and properties that are typical of elastic cartilage, demonstrating their potential for insertion into a patient.

The researchers state that in a future scenario, cartilage constructs could be clinically applied by using an MRI scan of a body part, such as the knee, as a blueprint for creating a matching construct. A careful selection of scaffold material for each patient's construct would allow the implant to withstand mechanical forces while encouraging new cartilage to organise and fill the defect.

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The above story is reprinted from materials provided by Institute of Physics (IOP).

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Tao Xu, Kyle W Binder, Mohammad Z Albanna, Dennis Dice, Weixin Zhao, James J Yoo, Anthony Atala. Hybrid printing of mechanically and biologically improved constructs for cartilage tissue engineering applications. Biofabrication, 2013; 5 (1): 015001 DOI: 10.1088/1758-5082/5/1/015001

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/n-Qlb40dWJM/121121210109.htm

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Wednesday, November 21, 2012

Healthy Hollywood: Wellness Wednesday ? Be An Urban Fitness ...


Billy Bush tackles the taxi obstacle at Men?s Health urbanathlon

Use common sense and don?t actually run across the tops of taxi cabs.

LOS ANGELES, CALIF. ??Healthy Hollywood?s good friends at Men?s Health magazine are challenging folks to the ultimate fitness race. Guys and girls nationwide are invited to compete in Men?s Health Urbanathlon. ?It is like a triatholon that uses the streets and landmarks of the city as part of the race. The 9.5 ? 11 mile course incorporates obstacles like hurdling over yellow taxi cabs, crawling under Subarus, tire-stutter stepping, over-under traffic barricade obstacles, chain link crawls?and stadium stair climbs,? reveals the Men?s Health team.

Access Hollywood?s own Billy Bush is the host of these fitness fests. So far, the races have been held in Chicago, New York and this weekend in San Francisco. Billy?s job is to warm up the over 5 thousand Urbanathletes. Let?s go, Billy!

But, if you can?t make it to the race, but still want to train like an urban champ, Men?s Health shares with Healthy Hollywood a do-it-yourself guide.

Here are three mini-workouts, each one inspired by the Urbanathlon, which feature long runs interspersed with muscle challenges. Workout 1 will train you for sustained effort, while the other two will build aerobic capacity and stimulate fat loss. Complete each routine once a week. Also, add one challenge to workouts 2 and 3. You?ll inject variety into your training time as you have more fun and achieve better results.

Workout 1

Step 1: Run 2 miles.

Step 2: Find a hill and run up 50 yards at about 80 percent of your sprinting pace. Walk back to the starting point. Do this a total of 10 times.

Step 3: Run 2 more miles.

Each week, add a quarter mile to Step 1 and to Step 3 until you build up to 6 miles total.

Workout 2

Step 1: Do a 400-yard sprint, timing yourself with a stopwatch. Try to run at the fastest pace you can maintain from start to finish.

Step 2: Rest for the same amount of time it took you to do the sprint.

Step 3: Add in Challenge 1, 2, or 3

Step 4: Rest for the same amount of time you rested in Step 2.

Step 5: Repeat three times, for a total of four rounds. Each week, add one round (including challenge) until you build up to eight rounds.

Workout 3

Step 1: Do an 800-yard sprint, timing yourself with a stopwatch. Try to run at the fastest pace you can maintain from start to finish.

Step 2: Rest for twice the amount of time it took you to do the sprint.

Step 3: Add in Challenge 1, 2, or 3 (on the next page).

Step 4: Rest for 60 seconds.

Step 5: Repeat three times, for a total of four rounds. Each week, add one round until you build up to eight rounds.

Challenge 1

Perform 1 set of each exercise below and then rest for 30 seconds. Repeat once, until you?ve done a total of 2 sets of each exercise.

Exercise 1: Jumping chinup

Stand beneath a chinup bar and, in one movement, jump up, grab the bar with an underhand grip, and pull your chest to the bar. (The momentum of your jump will help pull you up.) Do 2 reps.

Exercise 2: Reverse burpee

From a standing position, simultaneously squat down and lean forward, and then move straight into a pushup position. Lower your chest to the floor, and in one fluid movement, explosively push yourself back up and into a standing position. Do 10 reps.

Challenge 2

Do 1 set of each of the following exercises. Then go back to your workout.

Exercise 1: Walking lunge

Start with your hands behind your head (as if you?re being arrested). Keeping your torso upright, step forward with your left leg and lower your body straight down until your left knee is bent at least 90 degrees. Push your left heel into the ground, and step forward to a standing position. Then repeat with your right leg. Continue until you?ve traveled a total of 50 yards.

Exercise 2: Bear crawl

Assume a pushup position with your body in a straight line from your head to your ankles. (If this feels more like a lizard position to you, feel free to call it the iguana crawl.) Now move your right hand forward a few inches, and bring your left knee as close to your chest as you can without allowing the position of your torso to change or your lower back to round. That?s the starting position. Crawl forward by switching the positions of your arms and feet, moving your opposite arm and leg with each ?step.? Continue until you?ve traveled a total of 50 yards.

Challenge 3

Do 1 set of each exercise. Then rest 60 seconds and repeat. Once you?ve done two rounds, return to your sprints.

Exercise 1: Stepup

Stand facing the seat of a park bench. Place your left foot on it?or on another object of similar height?and put your hands behind your head. Push your heel into the bench as you push your body up onto the bench until your left leg is straight. (Don?t rest your right leg on the bench at the top; instead, hold it in the air.) Lower yourself to the ground. That?s 1 rep. Do 20 reps, and then repeat with your right leg.

Exercise 2: Bulgarian split squat

Stand a couple of feet from a park bench, with your back to the seat. Bend your right leg and place the top of your right foot on the bench as you place your hands behind your head. This is the starting position. Keeping your torso upright, bend your left leg and lower your body until your left leg is bent at least 90 degrees. Push your body back to the starting position. That?s 1 rep. Do 20 reps, and then switch legs and repeat.

For more information, check out?www.menshealthurbanathlon.com

? Terri MacLeod

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Source: http://insidefirst.me/2012/11/21/healthy-hollywood-wellness-wednesday-be-an-urban-fitness-warrior/

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Web design: KDR Creative Media - The Rod "Muniklip" Mosby Blog

If you have a business in Surrey that that you want to set up, you would know by now that the World Wide Web is one of the more formidable platforms through which you can market your services or products and at the same time get in touch with a better audience market than you ever thought was possible. Today, with the support of a website and basic marketing, you will have a way to set up your business on the net and drive your sales through the roof. When you choose for a web site design in Surrey to build up your online presence, you can be sure to get the best of what money can purchase.

Many a times, small business people decide to choose for a cheaper route and obtain web design companies in Surrey to design substandard sites for them. This in turn reflects poorly of their business and creates a sense of unprofessionalism about the business which they manage. If you are thinking about setting up a web site design for your small business in Surrey, then it really is strongly suggested that you seek professionals to manage your site. By the end of the day, you would need exactly what you are paying for and selecting for a professional web site design company in Surrey would be the perfect way to start it. If you do decide on buying a low priced design, you are only creating a chance for your company to sink. Most clients are impressed by having an online company just if they see a professional and well organized design on their service web site. Defectively constructed sales pages and product or sales descriptions directly affects business. It is therefore imperative that you select for a web site design firm in Surrey to be careful of your needs in a professional manner that can be depending on your requirements.

There are a number of web site design Surrey businesses that offer their services at substantially affordable rates. These types of organizations design web pages in HTML/CSS. Which means that you could have not a lot of control on the development of your pages. The moment you add a brand new service or product to your online business catalogue, you would need to shell out money again to have the web site updated. If you do not mind spending money over and over again, then you can go for it. Nevertheless, if you are looking at saving up on finances in the long run, you would be satisfied to know that very few web site design studios in Surrey that can offer you with a whole content management system which you can use to update your products and services.

The best content management system (CMS) available today is WordPress. WordPress promises to give you absolute get a handle on over your sites in order that you can update it whenever and wherever you want. Web site design companies in Surrey will design the CMS according to your specifications and provide you with log-in information to the WordPress CMS. The moment you opt for a web site design in Surrey to be careful of your small enterprises web design, you may also want to opt for marketing. SEO is a complicated marketing strategy which only a few Surrey web site design companies have already been in a position to understand. With the aid of search engine optimization (Search Engine Optimization), you will be able to control the search engine placements of your online business. This basically means that individuals that search for the products or services on leading search engines such as for instance Google, Bing and so on are certain to get to see your website first before anyone else's.

To help determine what SEO is, only search it. Finally, when all is prepared, a web site design Surrey Business will allow you to set up a PPC (Pay Per Click) campaign. Through the PPC campaign, you will be able to generate more visitors to your WordPress site and transform them in to sales. There are always a couple of technicalities with a PPC campaign which web site design companies for small businesses in Surrey should be able to assist you with. Fact of the subject is that good websites usually do not cost the planet earth. They have been affordable to a certain degree. When it comes to obtaining a complete and comprehensive online CMS to manage your website for you, give your complete flexibility in updating, modifying and adding products and marketing your site on the internet, spending around APS1,500 seems just like quite a good deal. As soon as you put up a CMS WordPress web site, you are certain to think it is favorable to your business in terms of its operations and financial returns. Mike Boulton works at wey2creative internet site design and optimisation in Weybridge, Surrey web design surrey. Content managed web sites beginning with 1,500 pounds.

Source: http://muniklip1.blogspot.com/2012/11/web-design-kdr-creative-media.html

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Australians find drugs worth $246M in steamroller

This photo released by the Australian Federal Police shows a steamroller which was used to hide drugs by two men in Sydney, Australia, Wednesday, Nov. 21, 2012. The Australian Federal Police said Wednesday that they arrested a Canadian man and a U.S. man after officers had seized 350kg (770 pound) of cocaine and methamphetamine hidden inside the steamroller shipped from China. (AP Photo/Australia Federal Police)

This photo released by the Australian Federal Police shows a steamroller which was used to hide drugs by two men in Sydney, Australia, Wednesday, Nov. 21, 2012. The Australian Federal Police said Wednesday that they arrested a Canadian man and a U.S. man after officers had seized 350kg (770 pound) of cocaine and methamphetamine hidden inside the steamroller shipped from China. (AP Photo/Australia Federal Police)

This Wednesday, Nov. 21, 2012 photo supplied by the Australian Federal Police shows small portion of a US$246 million drug haul seized in Sydney. The Australian Federal Police said Wednesday that they arrested a Canadian man and a U.S. man after officers had seized 350kg (770 pound) of cocaine and methamphetamine hidden inside a steamroller shipped from China. (AP Photo/Australia Federal Police)

(AP) ? Australian police seized 237 million Australian dollars ($246 million) worth of cocaine and methamphetamine found inside a steamroller shipped from China.

Australian Federal Police said Wednesday that they arrested a Canadian man and a U.S. man in Sydney after finding 350 kilograms (770 pounds) of cocaine and meth. The men were charged with importing drugs and face a maximum of life in prison if convicted.

It was the police agency's second major drug bust in a week. On Friday, police said officials had tracked down a boat carrying 200 kilograms (440 pounds) of cocaine to Australia after it ran aground in the small island nation of Tonga. A corpse was found on board. Officials are trying to determine the cause of death.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/aa9398e6757a46fa93ed5dea7bd3729e/Article_2012-11-20-Australia-Steamroller%20Drugs/id-3c6f429f1f9f4937899f118861569bf9

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Some Easy Ways To Grow Through Personal Development ...

Something may have happened recently that made you realize you need to change your behavior before losing those that are closest to you. You may find yourself wondering where to begin in changing your habits. You?ll find the techniques you need to change yourself for the better in the article below.

Your own personal development goals need to be specific so that they can help pave the road towards success. Defining your goals and researching what you can do to get there is the key to success. Doing so will allow you to realize success more quickly and meet all challenges.

Recognizing your limits when performing physical tasks can actually help you meet your goals. Trying your hardest and doing your best are important, but not important enough to ignore the warning signs of an impending limit. Your health and your body are the most important things, so always take care of them when you are pursuing a goal. Your personal development will suffer greatly if you sacrifice your health.

TIP! As part of your personal development, you should constantly try to have love be the driving force behind your faith. Faith seldom exists without the accompanying emotion of love.

Since nobody?s perfect, you?re going to fall off your diet plan sometimes and eat junk food instead of a healthy meal. Stress hurts your body as much as a large slice of high calorie pie, so take it all in stride.

Write something to pep yourself up. List all of your good qualities on a postcard. Keep this inspirational card with you at all times. Better yet, read the list out loud while recording yourself. What are the benefits of this?

Always remember as you work on developing yourself that you deserve to be better, and that it will benefit you more than anyone else. Always remember that you owe yourself your best effort. If you make every effort to improve, then you have nothing to regret.

TIP! You should approach life with modesty and wisdom. Keep an open mind and learn from new situations you encounter.

When working on your personal development, it is often helpful to see what others have done. The most obvious way to avoid pitfalls in both career and personal matters is to know what those pitfalls are and find out how other people avoided them. Reading about the lessons they have learned will have a positive impact on your own self improvement.

Learning to take controlled risks could bring you happiness. Being a little too risk-averse carries its own dangers, because someone who avoids failure or rejection at all costs can wind up feeling safe, but unsatisfied. Risk taking is courageous, which is a necessary quality in finding happiness.

Create goals that you can accomplish and live the life you love. If you work on your weaknesses, you can better yourself.

TIP! To get the most from your personal development efforts, be sure to aim high and value what is best. Therefore, you must value your best and make it an important aspect of your life.

True leaders are humble as they exercise their power. When rebukes are necessary, be gentle yet firm, and keep in mind that you must be able to serve to be able to lead effectively. A successful leader is one who demonstrates integrity and virtue as an example to others.

Always work towards your personal best. That passion of yours can put you on the road to success. While it is almost impossible to be the best at everything we do, aspiring to inspire other people is an admirable and worthy goal for oneself. Do your best to become a leader in your industry, as it will give your self-esteem a boost.

Every champion needs a coach, so get someone to help you. All champions have awesome coaches or mentors behind them, and this is very important. It is important for people who are educated in a certain field to pass on their knowledge to people entering the field. How can people achieve their best if this doesn?t happen? Everyone who is great at something has had help getting to where they are.

TIP! Know the obstacles you face before you hit them. Figuring this out is daunting for most people.

Getting and staying healthy is one of the most important parts of personal development. Exercising and eating nutritious foods are core to a healthy lifestyle, but you also need to be able to stay with your regimen. If your health is a priority, you have a better chance of feeling your best and therefore being a better contributor in other aspects of your life.

It is possible to deal with the tough situations that arise in everyone?s life without becoming overly emotional. Learning ways to maintain your composure when stressed will help boost your self-esteem, and help you triumph under any circumstance. Make the time to stop and breathe.

When you feel anger start to boil over, stop before you react and count to ten. Maybe take a short walk, breathe deeply, and concentrate on peaceful thoughts. Keeping what you say focused on the topic at hand can stop words being said out of pure anger.

TIP! When dealing with personal development, not making a decision means forgoing an opportunity. Do not be afraid to make decisions, even if you are not as well-informed as you could be.

Strive to increase the time you spend working as much as possible in order to accomplish more. One thing that you should do is to take frequent breaks from your tasks. Although it sounds counterproductive, taking breaks when working actually allows to to get more accomplished, because you aren?t getting burnt out. The breaks allow you a chance refresh yourself and work harder.

Stress is an enemy of happiness. When our mind is stressed, our body suffers. In order to reach your goals, the stress in your mind must be destroyed. Allow yourself a set time during each day that you can relax and empty your mind. This time of rejuvenation can help you feel better about yourself, and give you more peace at heart.

Do not go shopping for comfort. If you find yourself shopping out of habit, take up a hobby to replace the time spent shopping. You can relieve stress, reduce credit card bills and enjoy your time much more.

TIP! Exercise is for everyone, not just people who are trying to lose a few pounds. There are countless physical benefits to exercising.

If you don?t take care of yourself, you won?t be able to take care of others. Whatever point you may be at on your journey, it is important to properly care for yourself.

Always aim to keep self-discipline a priority as you work on bettering yourself. Learn to develop a strong sense of self control. Learn to resist the desires to overindulge yourself in food, drink, and other physical desires. You can keep vices from harming you in body and spirit if you learn to control yourself and resist them.

Seek out those with similar positive attitudes. Like-minded people will help strengthen your resolve while reinforcing positive attitudes.

TIP! Ego and self esteem can suffer as a result of failure when one is striving to make strides in the area of personal development. Failure is just a learning experience incognito.

A positive attitude will do wonders for your personal growth. When you carry a poor attitude, it will directly affect your mood and develop a negative aura. Maintain a positive approach to life in order to reach your goals.

Personal development does not happen quickly, as this article has shown. If you apply consistent time and effort, you should be rewarded by seeing positive changes in yourself. Follow these tips to make starting out a bit easier.

Figure out what you want your life to be and do what it takes to accomplish it. If you sit around wishing for a certain kind of life and don?t act toward making that life reality, then you will obviously never have that life. Take action, and turn your dreams into reality.

TIP! You should work on ensuring that each day is an improvement over the previous one. Push yourself to pursue every opportunity for improvement.

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Tuesday, November 20, 2012

'Twilight' Breaks The Bank Over The Weekend

FROM MTV NEWS "The Twilight Saga" went out with a bang this past weekend, when "Breaking Dawn - Part 2" debuted with $141.3 million, making the eight biggest opening weekend of all time. That figure just nearly missed the record for the series, which still belongs to "New Moon" with $142.8 million. But not every [...]

Source: http://moviesblog.mtv.com/2012/11/19/twilight-breaking-dawn-2-box-office/

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